Looking back on Dissemination: Manon Babise at the SFM Annual Congress

As we reflect on a rich year of scientific outreach within the Yellow4FLAVI consortium, we are proud to look back on the contribution of Manon Babise, PhD student in Dr. Jacques Dutrieux’s lab at INSERM Institut Cochin, who presented her work at the Annual Congress of the Société Française de Microbiologie (SFM) last September.

🦟 Manon delivered an oral communication entitled "Decoding the short-term immune response induced by Yellow Fever Virus in the human skin", presenting the first results from the IMMUNOVAX human cohort.

What the research is about

When a vaccine is administered, the skin is the very first barrier it encounters — and yet the early immune events taking place at this interface remain poorly understood. Manon Babise’s work sheds light on precisely this: what happens immunologically in human skin in the short term following yellow fever vaccination?

By characterizing these early local immune responses in situ in humans, this research provides a unique window into the mechanisms of protection induced by the yellow fever vaccine. These findings not only deepen our fundamental understanding of vaccine-induced immunity but also open exciting perspectives for optimising vaccination strategies — including the route of immunisation.

💡 Key learning: the skin is not just a passive barrier — it is an active immunological player. Understanding what unfolds at the site of injection, and how quickly, may hold the key to better vaccine design and delivery strategies.

A wonderful milestone for Manon and a strong contribution to Yellow4FLAVI's growing body of evidence. Congratulations! 👏🦟